Article
Leber's hereditary optic neuropathy in Thailand.
Japanese journal of ophthalmology - 1 Jan 2000
Chuenkongkaew W L, Lertrit P, Poonyathalang A, Sura T, Ruangvaravate N, Atchaneeyasakul L, Suphavilai R
Abstract excerpt
PURPOSE: To study the clinical features of Leber's hereditary optic neuropathy (LHON) in Thai patients as compared with patients in the United States, Europe, and other Asian countries. METHODS: The blood mitochondrial DNA of patients from 19 Thai pedigree families was studied for LHON mutation by restriction enzyme analysis. RESULTS: Mitochondrial mutation at nucleotide position 11778 was detected in 37 affected...
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