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Article

Blockade of CD14 aggravates experimental shigellosis.

Journal of endotoxin research - 1 Jan 2001

Wennerås C, Ave P, Huerre M, Arondel J, Ulevitch R, Mathison J, Sansonetti P

Abstract excerpt

Shigella infections lead to severe inflammation associated with destruction of colonic mucosa. We assessed the effect of in vivo blockade of CD14 on the outcome of experimental Shigella infection in rabbits. A total of 17 rabbits were divided into two groups: 8 received a single i.v. dose of anti-rabbit CD14 monoclonal antibody prior to infection with an invasive Shigella flexneri strain; the remainder served as...

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Source

Identifiers

PMID: 11753214

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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