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Article

Novel genetic etiologies of severe congenital neutropenia.

Current opinion in immunology - 1 Oct 2009

Boztug Kaan, Klein Christoph

Abstract excerpt

Severe congenital neutropenia (SCN) comprises a heterogenous group of primary immunodeficiency disorders collectively characterized by paucity of mature neutrophils. In recent years, progress has been made with respect to the elucidation of genetic causes underlying syndromic and non-syndromic variants of SCN. Most cases of autosomal dominant SCN are associated with mutations in the neutrophil elastase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19782549
DOI: 10.1016/j.coi.2009.09.003

Genes

ELANE
GFI1

Provenance

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