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Article

Glucocorticoids manifest androgenic activity in a cell line derived from a metastatic prostate cancer.

Cancer research - 15 Dec 2001

Chang C Y, Walther P J, McDonnell D P

Abstract excerpt

The pathophysiological mechanism(s) by which androgen independence develops in prostate cancer remains to be determined. The identification in many prostate cancer specimens of a mutant androgen receptor, T877A, with altered ligand specificity has provided an explanation for some treatment failures. The T877A mutant androgen receptor recognizes a number of nonandrogenic compounds, including certain estrogens,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms, Hormone-Dependent

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Share to Receptors, Androgen

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Source

Identifiers

PMID: 11751389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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