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Article

Conversion of oxacillin-resistant staphylococci from heterotypic to homotypic resistance expression.

Antimicrobial agents and chemotherapy - 1 Jan 2002

Finan J E, Rosato A E, Dickinson T M, Ko D, Archer Gordon L

Abstract excerpt

Staphylococci that acquire the mecA gene are usually resistant to beta-lactam antibiotics (methicillin or oxacillin resistance). mecA encodes a penicillin-binding protein (PBP 2a) that has a reduced affinity for beta-lactams. In some isolates with methicillin or oxacillin resistance, only a small proportion (< or =0.1%) of the population expresses resistance to > or =10 microg of oxacillin per ml (heterotypic...

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Identifiers

PMID: 11751106
DOI: 10.1128/AAC.46.1.24-30.2002
PMCID: PMC126971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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