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Article

mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis.

Antimicrobial agents and chemotherapy - 1 Mar 2005

Knobloch Johannes K-M, Jäger Sebastian, Huck Jörn, Horstkotte Matthias A, Mack Dietrich

Abstract excerpt

A lack of sigma(B) activity reduces methicillin resistance in heterogeneous Staphylococcus epidermidis 1057, whereas inactivation of the anti-sigma factor RsbW switched the phenotype to homogeneous expression of resistance. Oxacillin induction of mecA transcription is reduced in a sigma(B)-negative strain. However, mecA is not involved in the switch of expression phenotype.

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Identifiers

PMID: 15728932
DOI: 10.1128/AAC.49.3.1216-1219.2005
PMCID: PMC549230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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