Article
Correlation of hepatitis B virus load with loss of e antigen and emerging drug-resistant variants during lamivudine therapy.
Journal of medical virology - 1 Dec 2001
Zöllner B, Schäfer P, Feucht H H, Schröter M, Petersen J, Laufs R
Abstract excerpt
It remains unclear whether sequential assessment of hepatitis B virus (HBV) load during lamivudine therapy can predict the loss of hepatitis B e antigen or emergence of drug-resistant variants. Therefore, a longitudinal study was carried out in 28 consecutive patients with chronic hepatitis B who started lamivudine therapy for a median of 12 months (range, 6-31). HBV DNA copy numbers were determined at 3-month...
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