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Article

Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants.

The Journal of biological chemistry - 1 Mar 2002

Chen Yi-Hung, Chen Annie P-C, Chen Chao-Tsen, Wang Andrew H-J, Liang Po-Huang

Abstract excerpt

Undecaprenyl pyrophosphate synthase (UPPS) catalyzes the consecutive condensation reactions of eight isopentenyl pyrophosphate (IPP) with farnesyl pyrophosphate (FPP) to generate C(55) undecaprenyl pyrophosphate (UPP). In the present study, site-directed mutagenesis, fluorescence quenching, and s...

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Source

Identifiers

PMID: 11744728
DOI: 10.1074/jbc.M110014200

Genes

IPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11744728-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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