Article
Sucrose transport through maltoporin mutants of Escherichia coli.
Protein engineering - 1 Nov 2001
Van Gelder P, Dutzler R, Dumas F, Koebnik R, Schirmer T
Abstract excerpt
Maltoporin (LamB) and sucrose porin (ScrY) reside in the bacterial outer membrane and facilitate the passive diffusion of maltodextrins and sucrose, respectively. To gain further insight into the determinants of solute specificity, LamB mutants were designed to allow translocation of sucrose, which hardly translocates through wild-type LamB. Three LamB mutants were studied. (a) Based on sequence and structure...
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