Article
Recurrent miscarriage and variant alleles of mannose binding lectin, tumour necrosis factor and lymphotoxin alpha genes.
Clinical and experimental immunology - 1 Dec 2001
Baxter N, Sumiya M, Cheng S, Erlich H, Regan L, Simons A, Summerfield J A
Abstract excerpt
Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA) are associated with increased severity of infection. Studies have associated recurrent miscarriage with low serum mannose binding lectin concentrations and premature membrane rupture and preterm delivery with elevated...
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