Article
Loss of heterozygosity of the NOS3 dinucleotide repeat marker in atherosclerotic plaques of human carotid arteries.
Atherosclerosis - 1 Dec 2001
Grati F R, Ghilardi G, Sirchia S M, Massaro F, Cassani B, Scorza R, De Andreis C, Sironi E, Simoni G
Abstract excerpt
We have investigated 28 atherosclerotic plaques of human carotid arteries with a panel of 39 microsatellite markers for the presence of LOH. The objective of this research was to verify if LOH, described in association with tumorigenic process, could be involved also in benign fibroproliferative disease. Seventy percent of samples demonstrated allelic imbalance: 50% of cases showed LOH at a minimum of one locus,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.