Article

The effection of gene variation in Familial

2026-08-24

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disorder characterized by significantly elevated levels of low-density lipoprotein cholesterol (LDL-C) in the blood, which increases the risk of atherosclerotic cardiovascular diseases (ASCVD). It is usually accompanied by tendinitis xanthomatosis and a family history of early-onset coronary heart disease. Mutations in LDLR, PCSK9, and APOB are the main pathogenic ba...

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Literature Corpus work: ae89105f-3ab4-54f1-a980-bd21f4dfc727
DOI: 10.54097/pq337c45

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