The effection of gene variation in Familial

Abstract excerpt

Familial hypercholesterolemia (FH) is a genetic disorder characterized by significantly elevated levels of low-density lipoprotein cholesterol (LDL-C) in the blood, which increases the risk of atherosclerotic cardiovascular diseases (ASCVD). It is usually accompanied by tendinitis xanthomatosis and a family history of early-onset coronary heart disease. Mutations in LDLR, PCSK9, and APOB are the main pathogenic ba...

Topics

Open a Topic to create a Post that cites this publication.

• Cholesterol and Lipid Metabolism
• Dermatological and Skeletal Disorders
• Lipoproteins and Cardiovascular Health

Identifiers and source

Literature Corpus work

ae89105f-3ab4-54f1-a980-bd21f4dfc727

DOI

10.54097/pq337c45