Article
The genetics of migraine.
The Lancet. Neurology - 1 Sept 2002
Ducros Anne, Tournier-Lasserve Elisabeth, Bousser Marie-Germaine
Abstract excerpt
The search for genes involved in the pathophysiology of migraine poses major difficulties. First, there is no objective diagnostic method to assess the status of the individuals studied. Second, migraine is a polygenic multifactorial disorder. Familial hemiplegic migraine (FHM) is the only known autosomal dominant subtype of migraine. In half the families with FHM who have been studied, there are mutations in the...
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