Article
[Clinical utility of drug resistance testing].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 2002
Sugiura Wataru
Abstract excerpt
Emergence of drug resistant HIV-1 is one of the major causes of the anti-retrovirus treatment failure. There are two types of clinical tests to identify the drug resistance. One is nucleotide sequencing of the drug target genomes (genotyping) and the other is measuring drug susceptibility of patient derived HIV-1 in vitro (phenotyping). Several retrospective studies have shown correlation between drug resistance...
Topics
- Anti-HIV Agents
- Drug Resistance, Viral
- Genotype
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Microbial Sensitivity Tests
- Phenotype
- Sequence Analysis, DNA
