Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epitope mapping of four monoclonal antibodies specific for the human RhD antigen.

Immunology letters - 1 Jan 2002

Nickerson Lise, Wiersma Erik J

Abstract excerpt

RhD is a highly immunogenic erythrocyte membrane protein, implicated in hemolytic disease of the newborn and other hemolytic disorders. Anti-RhD antibodies are used in the treatment of such disease states. Six mutant forms of recombinant RhD were stably expressed in K562 cells, and these cells were used to investigate epitope specificities of four anti-RhD monoclonal antibodies (mAbs). Amino acid substitutions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibody Specificity
Share to Epitope Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Glycoproteins

Share to K562 Cells

Share to Oncogene Proteins, Fusion

Share to Rh-Hr Blood-Group System

Source

Identifiers

PMID: 11716963
DOI: 10.1016/s0165-2478(01)00297-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epitope mapping of four monoclonal antibodies specific for the human RhD antigen.PMID 11716963Read ↗

Site-directed mutagenesis of the human D antigen: definition of D epitopes on the sixth external domain of the D protein expressed on K562 cells.Semantic proximity Read ↗

Genetic and Immunological Properties of Phage-Displayed Human Anti-Rh(D) Antibodies: Implications for Rh(D) Epitope TopologySemantic proximity Read ↗

Serological studies of monoclonal RH antibodies with RH1 (D), RH2 (C), RH3 (E) and RH5 (e) variant RBCs.Semantic proximity Read ↗

Tentative model for the mapping of D epitopes on the RhD polypeptide.Semantic proximity Read ↗

A human monoclonal anti-D antibody which detects a nonconformation-dependent epitope on the RhD protein by immunoblot.Semantic proximity Read ↗

Site directed mutagenesis of the human Rh D antigen: molecular basis of D epitopes.Semantic proximity Read ↗

Molecular basis of the D variant phenotypes DNU and DII allows localization of critical amino acids required for expression of Rh D epitopes epD3, 4 and 9 to the sixth external domain of the Rh D protein.Semantic proximity Read ↗

Immunochemical characterization of rhesus proteins with antibodies raised against synthetic peptides.Semantic proximity Read ↗

Insights into anti-D formation in carriers of RhD variants through studies of 3D intraprotein interactions.Semantic proximity Read ↗

Reduced RhD antigen expression caused by two novel RHD variant alleles.Semantic proximity Read ↗

A structural model for 30 Rh D epitopes based on serological and DNA sequence data from partial D phenotypes.Semantic proximity Read ↗

Molecular cloning of RhD cDNA derived from a gene present in RhD-positive, but not RhD-negative individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.