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Article

HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression

1 Feb 2002

Abstract excerpt

At present, HOXC13 is the only member of the HOX multigene family that produces a fragile hair phenotype when mutated or overexpressed in mice. To determine whether hair keratin genes are targets for this transcription factor, we analyzed the HOXC13 responsiveness of human hair keratin genes, whose expression matched that of nuclear HOXC13, immunologically revealed in cells of the lower hair-forming compartment...

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PMID: 11714694
DOI: 10.1074/jbc.m101616200

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