Article
The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus).
BMC genomics - 23 Aug 2018
Wang Shanhe, Luo Zhixin, Zhang Yuelang, Yuan Dan, Ge Wei, Wang Xin
Abstract excerpt
BACKGROUND: During hair growth, cortical cells emerging from the proliferative follicle bulb rapidly undergo a differentiation program and synthesize large amounts of hair keratin proteins. In this process, HOXC13 is one critical regulatory factor, proved by the hair defects in HOXC13 mutant mice and HOXC13 mutant patients. However, inconsistent conclusions were drawn from previous researches regarding the...
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