Article
Hair defects in Hoxc13 mutant mice.
The journal of investigative dermatology. Symposium proceedings - 1 Dec 1999
Godwin A R, Capecchi M R
Abstract excerpt
Hox genes encode transcription factors that are important during normal embryonic development of diverse organisms including vertebrates. In mammals, Hox genes are responsible for conferring regional identity in embryonic tissues, including the limb bud, the neural tube, the presomitic mesoderm and the intestinal tract. Recent studies have demonstrated expression of Hox genes in skin and hair follicles,...
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