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Molecular and genetic basis for thrombasthenic thrombopathia in Otterhounds

1 Nov 2001

Abstract excerpt

OBJECTIVES: To determine the molecular and genetic basis for thrombasthenic thrombopathia in Otterhounds and establish whether the defect would be best classified as type-I Glanzmann's thrombasthenia. ANIMALS: 57 dogs, including 13 affected Otterhounds, 23 carrier Otterhounds, 17 unaffected Otterhounds, and 4 clinically normal unrelated dogs of other breeds. PROCEDURE: Functional (platelet aggregation, clot...

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PMID: 11703027
DOI: 10.2460/ajvr.2001.62.1797

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