Article
Genomic approaches to research in pulmonary hypertension.
Respiratory research - 1 Jan 2001
Geraci M W, Gao B, Hoshikawa Y, Yeager M E, Tuder R M, Voelkel N F
Abstract excerpt
Genomics, or the study of genes and their function, is a burgeoning field with many new technologies. In the present review, we explore the application of genomic approaches to the study of pulmonary hypertension (PH). Candidate genes, important to the pathobiology of the disease, have been investigated. Rodent models enable the manipulation of selected genes, either by transgenesis or targeted disruption....
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