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Article

[Pulmonary hypertension: pathophysiology, genetics and functional genomics].

Der Internist - 1 Jul 2005

Eickelberg O, Seeger W

Abstract excerpt

Novel discoveries of the genetic basis of pulmonary hypertension have recently inspired a whole new area of research in pulmonary medicine. The finding that germ-line mutations in the BMPR2 locus, encoding a transmembrane receptor of the TGF beta superfamily, are the cause for familial and partly idiopathic pulmonary arterial hypertension has provided new clues for our understanding of this complex, yet highly...

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Share to Bone Morphogenetic Protein Receptors, Type II
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15918053
DOI: 10.1007/s00108-005-1431-8

Genes

BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Pulmonary hypertension: pathophysiology, genetics and functional genomics].PMID 15918053Read ↗

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Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertensionSemantic proximity Read ↗

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