Article
A molecular approach to the classification of von Willebrand disease.
Best practice & research. Clinical haematology - 1 Jun 2001
Schneppenheim R, Budde U, Ruggeri Z M
Abstract excerpt
The marked heterogeneity of von Willebrand disease was already recognized by von Willebrand in 1926. The accumulating knowledge of the different clinical phenotypes and the pathophysiological basis of the disease was translated into a classification that differentiated between quantitative and qualitative defects by means of quantitative and functional parameters and by analysing the electrophoretic pattern of...
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