Diagnosis of von Willebrand disease subtypes: implications for treatment.

Abstract excerpt

von Willebrand disease (VWD) is a complex congenital bleeding disorder that is characterized by different quantitative and/or qualitative defects in von Willebrand factor (VWF). The diagnosis of VWD remains a challenge to the treating physician because of clinical and laboratory variability; many patients are oligosymptomatic and no single laboratory test is entirely diagnostic. Thus, a combination of patient...

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