Article
Detection of mutations within the thymidine kinase gene of herpes simplex virus type 1 by denaturing gradient gel electrophoresis.
Journal of virological methods - 1 Jan 2002
Lu Qiaosheng, Hwang Ying T, Hwang Charles B C
Abstract excerpt
Denaturing gradient gel electrophoresis has been applied widely for the detection of mutation(s) and polymorphisms of various genes. It is shown that this system is also feasible for analyzing mutations in the thymidine kinase (tk) gene of herpes simplex virus type 1 (HSV-1). Thus, this system is applicable for examining whether a drug-resistant HSV-1 contains a tk mutation(s) or otherwise. This system can also...
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