Article
Statistical inference of sequence-dependent mutation rates.
Current opinion in genetics & development - 1 Dec 2001
Zavolan M, Kepler T B
Abstract excerpt
Several lines of research are now converging towards an integrated understanding of mutational mechanisms and their evolutionary implications. Experimentally, crystal structures reveal the effect of sequence context on polymerase fidelity; large-scale sequencing projects generate vast amounts of sequence polymorphism data; and locus-specific databases are being constructed. Computationally, software and...
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