Article
Inter- and intraindividual variability of riluzole serum concentrations in patients with ALS.
Journal of the neurological sciences - 15 Oct 2001
Groeneveld G J, van Kan H J, Toraño J S, Veldink J H, Guchelaar H J, Wokke J H, van den Berg L H
Abstract excerpt
All patients with amyotrophic lateral sclerosis (ALS) are treated with the same dose of riluzole: 50 mg twice daily. Reasonably large interindividual differences in clearance of the drug have been reported. The relatively small group of patients with high blood concentrations of riluzole has prob...
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