Article
Effect of polygenes on Xiong's transmission disequilibrium test of a QTL in nuclear families with multiple children.
Genetic epidemiology - 1 Nov 2001
Deng H W, Li J, Recker R R
Abstract excerpt
The transmission disequilibrium test (TDT), originally developed for mapping disease genes, has recently been extended to identify quantitative trait loci (QTL). For quantitative traits important for human health, generally multiple QTLs are involved. In the investigation of the statistical properties of the TDT, background polygenes (QTLs other than the QTL under test) generally have not been explicitly...
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