Article
[Mechanism of retroinhibition in e regulation of flavinogenesis in yeasts of genus Pichia].
Mikrobiologiia - 1 Jan 2000
Shavlovskiĭ G M, Logvinenko E M, Koltun L V
Abstract excerpt
The kinetics of the synthesis of a riboflavin (RF) precursor, 2,6-dihydroxy-5-amino-4-ribitylaminopyrimidine (DHARAP), was studied using the washed cells of RF-deficient mutants of Pichia guilliermondii R7G and Pichia ohmeri R32 with blocked lumasine synthetase. RF inhibited the synthesis of DHARAP while cycloheximide in the absence of RF had no effect on this process. The data suggest that flavins regulate the...
Topics
- Ascomycota
- Cycloheximide
- Flavins
- Mutation
- Pichia
- Riboflavin