Article
Macrolide resistance among invasive Streptococcus pneumoniae isolates.
JAMA - 17 Oct 2001
Hyde T B, Gay K, Stephens D S, Vugia D J, Pass M, Johnson S, Barrett N L, Schaffner W, Cieslak P R, Maupin P S, Zell E R, Jorgensen J H, Facklam R R, Whitney C G
Abstract excerpt
CONTEXT: Macrolide antibiotics, including erythromycin, clarithromycin, and azithromycin, are the mainstays of empirical pneumonia therapy. Macrolide resistance among Streptococcus pneumoniae, the most common cause of community-acquired pneumonia, is increasing in the United States. Whether resistance is a significant problem or whether macrolides remain useful for treatment of most resistant strains is unknown....
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