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Article

Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

Science (New York, N.Y.) - 21 Sept 2001

Ji Y, Zhang B, Van S F, Horn, Warren P, Woodnutt G, Burnham M K, Rosenberg M

Abstract excerpt

Comprehensive genomic analysis of the important human pathogen Staphylococcus aureus was achieved by a strategy involving antisense technology in a regulatable gene expression system. In addition to known essential genes, many genes of unknown or poorly defined biological function were identified. This methodology allowed gene function to be characterized in a comprehensive, defined set of conditionally...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11567142
DOI: 10.1126/science.1063566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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