Article
Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action.
Gene - 19 Sept 2000
Zhang L, Fan F, Palmer L M, Lonetto M A, Petit C, Voelker L L, St John A, Bankosky B, Rosenberg M, McDevitt D
Abstract excerpt
Selectively regulating gene expression in bacteria has provided an important tool for studying gene function. However, well-regulated gene control systems have been restricted primarily for use in laboratory non-pathogenic strains of bacteria (e.g. Escherichia coli, Bacillus subtilis). The development of analogous systems for use in bacterial pathogens such as Staphylococcus aureus would significantly enhance our...
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