Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1.

The EMBO journal - 17 Sept 2001

Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B

Abstract excerpt

The ternary complex factors (TCFs) Net, Elk-1 and Sap-1 regulate immediate early genes through serum response elements (SREs) in vitro, but, surprisingly, their in vivo roles are unknown. Net is a repressor that is expressed in sites of vasculogenesis during mouse development. We have made gene-t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Dilatation, Pathologic
Share to Early Growth Response Protein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium

Share to Immediate-Early Proteins

Share to Lymphatic System

Share to Vascular Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 11566878
DOI: 10.1093/emboj/20.18.5139
PMCID: PMC125619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11566878-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1.PMID 11566878Read ↗

Endothelial Erg Regulates Expression of Pulmonary Lymphatic Junctional and Inflammation Genes in Mouse Lungs Impacting Lymphatic TransportSemantic proximity Read ↗

Endothelial Erg Regulates Expression of Pulmonary Lymphatic Junctional and Inflammation Genes in Mouse Lungs Impacting Lymphatic TransportSemantic proximity Read ↗

Net , an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse developmentSemantic proximity Read ↗

Combinatorial function of ETS transcription factors in the developing vasculature.Semantic proximity Read ↗

Mouse models in the study of the Ets family of transcription factors.Semantic proximity Read ↗

Loss of ERG function causes lymphatic vessel malformations and primary lymphoedemaSemantic proximity Read ↗

Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1.Semantic proximity Read ↗

The human <i>FLT1</i> regulatory element directs vascular expression and modulates angiogenesis pathways <i>in vitro</i> and <i>in vivo</i>Semantic proximity Read ↗

Comparative gene array analyses of severe elastic fiber defects in late embryonic and newborn mouse aortaSemantic proximity Read ↗

Early growth response-1, a dynamic conduit in cardiovascular diseaseSemantic proximity Read ↗

ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease.Semantic proximity Read ↗

The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.