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Article

Toxic effect of rifampicin on human osteoblast‐like cells

1 Sept 2001

Abstract excerpt

We examined the effects of rifampicin on osteoblast-like cells derived from adult human bone in vitro. Cancellous bone was collected from five different individuals during elective orthopaedic operations and cultured in antibiotic-free media. Total DNA, 3H-thymidine incorporation and alkaline phosphatase (ALP) activity were measured after the cells were cultured for 4 days in media containing concentrations of...

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PMID: 11562146
DOI: 10.1016/s0736-0266(01)00022-5

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