Article
Genetic analysis of a variant luteinizing hormone in an infertile woman.
Archives of gynecology and obstetrics - 1 Aug 2001
Okuno A, Komori S, Sakata K, Nakata Y, Tsuji Y, Koyama K, Kameda T
Abstract excerpt
In a woman with infertility and an endometrial polyp, we analyzed the nucleotide sequence of the beta-subunit of her luteinizing hormone which showed anomalous immunogenecity in that it was recognized by time resolved-fluoroimmunoassay but not by immunoradiometric assay. The sequence analysis showed two substitutional mutations of beta-subunit Trp (TGG) to Arg (CGG) and Ile (ATC) to Thr (ACC). The variant...
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