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Article

Dual function of eIF3j/Hcr1p in processing 20 S pre-rRNA and translation initiation.

The Journal of biological chemistry - 16 Nov 2001

Valásek L, Hasek J, Nielsen K H, Hinnebusch A G

Abstract excerpt

eIF3j/Hcr1p, a protein associated with eIF3, was shown to bind to, and stabilize, the multifactor complex containing eIFs 1, 2, 3, and 5 and Met-tRNA(i)(Met), whose formation is required for an optimal rate of translation initiation. Here we present evidence that eIF3j/Hcr1p is an RNA binding protein that enhances a late step in 40 S ribosome maturation involving cleavage of the 20 S precursor of 18 S rRNA in the...

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Identifiers

PMID: 11560931
DOI: 10.1074/jbc.M106887200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dual function of eIF3j/Hcr1p in processing 20 S pre-rRNA and translation initiation.PMID 11560931Read ↗

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