Article
Identification of genes potentially involved in rupture of human atherosclerotic plaques.
Circulation research - 14 Sept 2001
Faber B C, Cleutjens K B, Niessen R L, Aarts P L, Boon W, Greenberg A S, Kitslaar P J, Tordoir J H, Daemen M J
Abstract excerpt
Although rupture of an atherosclerotic plaque is the major cause of acute vascular occlusion, the exact molecular mechanisms underlying this process are still poorly understood. In this study, we used suppression subtractive hybridization to make an inventory of genes that are differentially expressed in whole-mount human stable and ruptured plaques. Two libraries were generated, one containing 3000 clones...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.