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Article

Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction

29 Jun 2022

Abstract excerpt

Background Acute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of immune responses to plaque rupture. However, the specific circulating immune cell subsets that mediate inflammatory plaque rupture remain elusive. Methods Ten AMI patients were enrolled in our study (five with and five without plaque rupture;...

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PMID: 35844519
DOI: 10.3389/fimmu.2022.908815

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