Article
Simulating genealogies of selected alleles in a population of variable size.
Genetical research - 1 Aug 2001
Slatkin M
Abstract excerpt
An importance-sampling method is presented that allows the simulation of the history of a selected allele in a population of variable size. A sample path describing the number of copies of an allele that arose as a single mutant is generated by simulating backwards from the current frequency until the allele is lost. The mathematical expectation of a quantity or statistic is then estimated by taking averages over...
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