Article
Identification of a Y chromosome haplogroup associated with reduced sperm counts.
Human molecular genetics - 1 Sept 2001
Krausz C, Quintana-Murci L, Rajpert-De Meyts E, Jørgensen N, Jobling M A, Rosser Z H, Skakkebaek N E, McElreavey K
Abstract excerpt
In man, infertility is associated with microdeletions of specific regions of the long arm of the Y chromosome. This indicates that factors encoded by the Y chromosome are necessary for spermatogenesis. However, the majority of men with either idiopathic azoospermia or oligozoospermia have grossly intact Y chromosomes and the underlying causes of their infertility are unknown. We hypothesized that some of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.