Article
Y chromosome haplogroups: a correlation with testicular dysgenesis syndrome?
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2003
McElreavey Ken, Quintana-Murci Lluis
Abstract excerpt
Testicular dysgenesis syndrome encompasses low sperm quality, hypospadias, cryptorchidism and testicular cancer. Epidemiological studies and genetic data from familial cases suggest that testicular dysgenesis syndrome has a common etiology. The Y chromosome is known to encode genes that are involved in germ cell development or maintenance. We have therefore investigated if different classes of Y chromosomes in...
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