Article
Genetic diversity of Plasmodium falciparum infections in mild and severe malaria of children from Kampala, Uganda.
Parasitology research - 1 Apr 2013
Kiwuwa Mpungu Steven, Ribacke Ulf, Moll Kirsten, Byarugaba Justus, Lundblom Klara, Färnert Anna, Fred Kironde, Wahlgren Mats
Abstract excerpt
Diversity in parasite virulence is one of the factors that contribute to the clinical outcome of malaria infections. The association between the severity of Plasmodium falciparum malaria and the number of distinct parasite populations infecting the host (multiplicity of infection) or polymorphism within any of the specific antigen genes was investigated. The study included 164 children presenting with mild and...
Topics
- Child
- Child, Preschool
- Female
- Genetic Variation
- Genotype
- Humans
- Infant
- Malaria, Falciparum
- Male
- Plasmodium falciparum
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Protozoan Proteins