Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm.

doi:10.1074/jbc.M106962200

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Article

Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm.

The Journal of biological chemistry - 16 Nov 2001

Trent M S, Ribeiro A A, Doerrler W T, Lin S, Cotter R J, Raetz C R

Abstract excerpt

Polymyxin-resistant mutants of Escherichia coli and Salmonella typhimurium accumulate a novel minor lipid that can donate 4-amino-4-deoxy-l-arabinose units (l-Ara4N) to lipid A. We now report the purification of this lipid from a pss(-) pmrA(C) mutant of E. coli and assign its structure as undeca...

Topics

Amino Sugars
Anti-Bacterial Agents
Bacterial Proteins
Carbohydrate Sequence
Carbohydrates
Cell Nucleus
Cell-Free System
Chromatography
DEAE-Cellulose
Escherichia coli
Ethanolamines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydrolysis

Lipid A

Lipids

Magnetic Resonance Spectroscopy

Models, Chemical

Molecular Sequence Data

Mutation

Source

Open in PubMed

Identifiers

PMID: 11535605
DOI: 10.1074/jbc.M106962200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-11535605-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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