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Article

Divergent evolution in M6P/IGF2R imprinting from the Jurassic to the Quaternary.

Human molecular genetics - 15 Aug 2001

Killian J K, Nolan C M, Wylie A A, Li T, Vu T H, Hoffman A R, Jirtle R L

Abstract excerpt

M6P/IGF2R imprinting first appeared approximately 150 million years ago following the divergence of prototherian from therian mammals. Although M6P/IGF2R is clearly imprinted in opossums and rodents, its imprint status in humans remains ambiguous. It is also still unknown if M6P/IGF2R imprinting was an ancestral mammalian epigenotype or if it evolved convergently. We report herein that M6P/IGF2R is imprinted in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11532981
DOI: 10.1093/hmg/10.17.1721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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