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Article

KP4 fungal toxin inhibits growth in Ustilago maydis by blocking calcium uptake.

Molecular microbiology - 1 Aug 2001

Gage M J, Bruenn J, Fischer M, Sanders D, Smith T J

Abstract excerpt

KP4 is a virally encoded fungal toxin secreted by the P4 killer strain of Ustilago maydis. From our previous structural studies, it seemed unlikely that KP4 acts by forming channels in the target cell membrane. Instead, KP4 was proposed to act by blocking fungal calcium channels, as KP4 was shown to inhibit voltage-gated calcium channels in rat neuronal cells, and its effects on fungal cells were abrogated by...

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Identifiers

PMID: 11532143
DOI: 10.1046/j.1365-2958.2001.02554.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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