Article
An extracellular ligand increases the specific activity of the receptor-like protein tyrosine phosphatase DEP-1.
Oncogene - 23 Aug 2001
Sörby M, Sandström J, Ostman A
Abstract excerpt
Cellular growth, differentiation and migration is regulated by protein tyrosine phosphorylation. Receptor-like protein tyrosine phosphatases are thus likely to be key regulators of vital cellular processes. The regulation of these enzymes is in general poorly understood. Ligands have been identified only for a small subset of the receptor-like protein tyrosine phosphatases and in no case has upregulation of the...
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