Article
Predicted amino acid sequences for 100 JCV strains.
Journal of neurovirology - 1 Aug 2001
Cubitt C L, Cui X, Agostini H T, Nerurkar V R, Scheirich I, Yanagihara R, Ryschkewitsch C F, Stoner G L
Abstract excerpt
DNA sequence variation between JCV genotypes is confined largely to noncoding intergenic regions and introns. Nevertheless, evidence suggests that the amino acid sequence variations among the 8 genotypes of JCV can influence the potential for neurovirulence of the virus. In the current study, the amino acid sequences for 100 JCV genomes were translated and grouped into genotype families. Subtype consensus...
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