Article
Haplotype analysis of BRCA2 8765delAG mutation carriers in French Canadian and Yemenite Jewish hereditary breast cancer families.
Human heredity - 1 Jan 2001
Manning A P, Abelovich D, Ghadirian P, Lambert J A, Frappier D, Provencher D, Robidoux A, Peretz T, Narod S A, Mes-Masson A M, Foulkes W D, Wang T, Morgan K, Fujiwara T M, Tonin P N
Abstract excerpt
The BRCA2 8765delAG mutation was previously reported in hereditary breast cancer families of French Canadian and Yemenite Jewish descent. Haplotype analysis, using six microsatellite markers that span BRCA2 and two intragenic polymorphisms, was performed on 8765delAG mutation carriers to determine if there was evidence that the mutations were identical by descent. The alleles of the microsatellite markers most...
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