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Article

Prevalence of BRCA1 and BRCA2 Jewish mutations in Spanish breast cancer patients.

British journal of cancer - 1 Mar 1999

Díez O, Osorio A, Robledo M, Barroso A, Domènech M, Cortés J, Albertos J, Sanz J, Brunet J, SanRomán J M, Alonso M C, Baiget M, Benítez J

Abstract excerpt

We screened the 185delAG and 5382insC (BRCA1) and the 6174delT (BRCA2) mutation in 298 Spanish women with breast cancer. Two women (one with Sephardic ancestors) presented the 185delAG mutation and the same haplotype reported in Ashkenazim with this mutation. This suggests a common origin of the 185delAG in both Sephardic and Ashkenazi populations.

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Source

Open in PubMed Open full text

Identifiers

PMID: 10098775
DOI: 10.1038/sj.bjc.6690208
PMCID: PMC2362239

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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