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Article

Origin and distribution of the BRCA2-8765delAG mutation in breast cancer.

BMC cancer - 19 Jul 2007

Palomba Grazia, Cossu Antonio, Friedman Eitan, Budroni Mario, Farris Antonio, Contu Antonio, Pisano Marina, Baldinu Paola, Sini Maria C, Tanda Francesco, Palmieri Giuseppe

Abstract excerpt

BACKGROUND: The BRCA2-8765delAG mutation was firstly described in breast cancer families from French-Canadian and Jewish-Yemenite populations; it was then reported as a founder mutation in Sardinian families. We evaluated both the prevalence of the BRCA2-8765delAG variant in Sardinia and the putative existence of a common ancestral origin through a haplotype analysis of breast cancer family members carrying such...

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Identifiers

PMID: 17640379
DOI: 10.1186/1471-2407-7-132
PMCID: PMC1940259

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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