Article
Enterovirus antibody levels during the first two years of life in prediabetic autoantibody-positive children.
Diabetologia - 1 Jul 2001
Sadeharju K, Lönnrot M, Kimpimäki T, Savola K, Erkkilä S, Kalliokoski T, Savolainen P, Koskela P, Ilonen J, Simell O, Knip M, Hyöty H
Abstract excerpt
AIMS/HYPOTHESIS: We evaluated the role of enterovirus infections in the pathogenesis of Type I (insulin-dependent) diabetes mellitus by monitoring enterovirus antibody levels in prediabetic children who turned positive for diabetes-associated autoantibodies in a prospective birth cohort study. METHODS: Serial serum samples taken during prospective observation starting at birth were analysed for IgG and IgA class...
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